Windows Firewall is a program included with Windows that uses rules to control incoming and outgoing network traffic. It helps to protect your home network and keep your data secure from network threats.

Try to temporarily turn off the Windows Firewall and then make MobileSync connection again. If the connection attempt works, it is Windows Firewall which blocks the connection between MobileSync Station in Windows and MobileSync App in Android.

You can manually add new Inbound Rule in Windows Firewall to allow incoming connection request from MobileSync App in Android devices.

Follow below steps to add a new Inbound Rule in Windows Firewall

1. Navigate to Control Panel, System and Security and Windows Firewall.
2. Select Advanced settings in the left pane.
3. Right click Inbound Rules in the left pane.and select New Rule.
4. Select Port and click Next
5. Select TCP and enter 53180 for port number. If you have selected port number other than 53180 in settings of MobileSync Station, enter the same port number into the input box.
 6.  Select Allow the connection and click Next
 7. Select the network type as you see fit and click Next.
 8. Enter a meaningful name of this new rule and click Finish
 9. Click [START] button on MobileSync App main screen to connect to MobileSync Station again.